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Reference type: Book Chapter Authors: Andersson LI, Nicholls IA, Mosbach K Publication date: 1995 Chapter title: Antibody mimics obtained by noncovalent molecular imprinting. Chapter number: 6 Page numbers: 89-96. DOI: 10.1021/bk-1995-0586.ch006
Book title: Immunoassays of Agrochemicals
Abstract: Molecular imprinting is becoming increasingly recognized as a technique for the ready preparation of polymeric materials containing recognition sites of predetermined specificity. In many instances molecularly imprinted polymers show binding affinities approaching those demonstrated by antigen-antibody systems. The imprints are highly specific, with selectivity profiles comparable to those of antibodies often being observed. Imprinted polymers, with their extremely easy preparation from simple chemical components and ligand-selective recognition, may be regarded as effective and efficient mimics of biological antibodies. The use of polymer based antibody mimics in immunoassay-like techniques is discussed |