Abstract: A chemiluminescence reaction between soluble Mn(IV) and indapamide was found. An indapamide MIP was synthesized and its adsorption selectivity to indapamide in aqueous solution was evaluated. Using soluble Mn(IV)-formaldehyde-indapamide chemiluminesence system as detection system and the indapamide MIP as recognition material, a selective molecule imprinting-chemiluminesence method of determination of indapamide was established. The linearly response range of this method was from 2.0 x 10-8 to 5.0 x 10-6 g/mL with a linear correlation coefficient of 0.995. The detection limit was 8 x 10-9 g/mL. The relative standard deviation for 5.0 x 10-7 g/mL of indapamide solution was 3.5% (n = 9)
Template and target information: indapamide
Author keywords: Indapamide, Soluble Mn(IV), Molecule imprinting-chemiluminescence method

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