Abstract: Molecularly imprinted polymers(MIPs) were synthesized via(thermal) polymerization method with levofloxacin(LVFX) as template and methyacrylic acid as functional monomer.The UV and IR spectra(indicated) that the MIPs could recognize LVFX molecule through hydrogen-bond and ionic-bond interactions.Scatchard analysis showed that two kinds of recognition sites were formed,and the maximum apparent binding capacities were 9.76 μmol/g and 25.75 μmol/g,respectively.The selective adsorption of LVFX on MIPs could be completed in 10 min.On the basis of isothermal binding thermodynamics,the absorption to the(template) was spontaneous,and Δ Δ H=-1.18 kJ/mol and Δ Δ S=-0.27 J/(mol·K).
Template and target information: levofloxacin, LVFX
Author keywords: levofloxacin (LVFX), molecularly imprinted polymer, Scatchard analysis, thermodynamics

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