Editors: Ma LX, Wang CS, Yang WM
Publisher: Scientific.Net
Conference information: Advanced Polymer Processing

Abstract: Molecularly imprinted composite membranes for selective binding and permeation of roxithromycin were prepared by means of thermal initiated co-polymerization method using polysulfone ultra-filtration membranes as porous supports. Scanning electron microscope was utilized to visualize surface and cross-sections of the membranes to gain more better understanding in the analysis of imprinted layers deposited on PSF support membranes and differential scanning calorimetric was used for determining the thermal stability of the membranes. Static equilibrium binding and recognition properties of the imprinted and non-imprinted membranes to roxithromycin and its analogues in ethanol solution system were tested. The results showed that saturated binding capacity of imprinted membrane to roxithromycin was about 2.24++mol/g, higher than those of its analogues, and the selectivity factors of +¦ _RM/EM, +¦_RM/AM and +¦_RM/EE were 1.75, 2.46 and 2.67, respectively. The transport performances of the membranes were evaluated through kinetic filtration experiments. The separation mechanism of the roxithromycin imprinted membrane could be defined as facilitated permeation mechanism. -® (2010) Trans Tech Publications
Template and target information: roxithromycin
Author keywords: binding capacity, molecularly imprinted composite membranes, Roxithromycin, Thermal co-polymerization, Transport property

Tweet