Abstract: Focusing on polar components,similar compounds,homologue components and trace compounds in Traditional Chinese Medicine (TCM),novel strategies and material are developed for systematic separation and characterization of standard multi-component collectives from TCM.Solid phase for hydrophilic interaction chromatography is developing to separate polar components,resin-combination technique is suitable for similar compounds collection, multi-molecular imprinting technology is using to extract homologue components,and differential enriched strategy is applied to afford trace compounds.Also,multi modes and columns chromatography as well as their coupled technologies are applied to prepare standard compounds for library construction.All these works will elucidate the chemical constitution in TCM
Author keywords: Multi-component Chinese Medicine, Systematic separation strategy, Solid phase development, Homologue components

Tweet