Abstract: Abstract: A novel urea electrochemical sensor was constructed based on chitosan molecularly imprinted films which were prepared by potentiostatic electrodeposition of chitosan in the presence of urea followed by eluting with 0.1 M KCl. Various techniques were carried out to investigate the formation of molecularly imprinted polymer (MIP) films and the performance of the sensor. According to our expectation, the urea MIP electrochemical sensor showed excellent selectivity to urea among the structural similarities and co-existences, high linear sensitivity to urea in the range from 1.0 x 10-8 to 4.0 x 10-5 M with a detection limit of 5.0 x 10-9 M. Furthermore, the recovery ranged from 96.3 % to 103.3 % and therefore offered great potential for clinical diagnosis applications
Template and target information: urea
Author keywords: Electrochemical sensor, molecular imprinting technology, urea, chitosan

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