Abstract: OBJECTIVE: To establish a selective isolation method of imatinib mesylate using molecular imprinting technology. METHODS: The molecular imprinted polymer (MIP) was synthesized by bulk polymerization using imatinib mesylate as the template. The MIP was investigated for its recognition of imatinib mesylate by equilibrium absorption and solid-phase extraction. RESULTS: The MIP had specific absorbability to Imatinib mesylate. CONCLUSION: The MIP prepared in the study can be used for selective recognition and isolation of imatinib mesylate analogues from natural products
Template and target information: imatinib mesylate
Author keywords: Bulk polymerization, Imatinib mesylate, Molecularly imprinted polymers, selective recognition

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