Proceedings title: Advanced Materials Research
Editors: Zeng JM, Kim YH, Chen YF
Publisher: Scientific.net
Volume number: 399-401
Conference information: New Materials, Applications and Processes

Abstract: Thin-layer molecularly imprinted composite membranes for selective binding and permeation of levodropopizine were developed via thermal-initiated surface modification of polyvinylidene fluoride microfiltration membranes. ATR-FTIR was used to analyze the surface structures of these membranes. Binding experiments revealed that the saturated binding capacity of MICM was 75.746 μmol /g, nearly 3 times higher than that of NICM. Scatchard analysis showed that binding specificity of MICM was a result of multi-site binding to the template. The selective factor of LDPZ and 1-phenylpiperazine was 2.344 in competitive permeation studies. The permeation mechanism of LDPZ imprinted membranes could be inferred as facilitated permeation mechanism.
Template and target information: levodropopizine, LDPZ
Author keywords: binding property, composite membranes, Levodropopizine, permeation, PVDF

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