Reference type: Conference Proceeding Authors:Reddy KK, Gobi KV Publication date:2011 Article title: Artificial Biomolecular Recognition Element Based Sensor for Electrochemical Impedance Detection of Creatinine. Page numbers: 25-29 Alternative URL:http://www.ipcbee.com/vol25/6-ICNB2011_Q00018.pdf
Publisher: IACSIT Press City: Singapore ISBN: 2010-4618 Volume number: 25 Conference information: Proceedings of the 2011 International Conference on Nanotechnology and Biosensors
Abstract: A novel molecular imprinted polymer (MIP) based electrode has been investigated for electrochemical impedimetric detection of creatinine. Magnitude of impedance was measured in a frequency range of 10 mHz to 60 KHz in the presence and absence of creatinine. Based on the best-fitting equivalence circuit analysis, it was found that the charge-transfer impedance of the electrode increased by the addition of creatinine and increased further with increasing concentrations. Control experiments with non-imprinted polymer (NIP) electrode showed that the sensor is totally non-responsive to creatinine. The low-detectionlimit of the impedance sensor is 50 ng/mL. The sensor surface of the fabricated MIP electrode is easily renewable for repeated cyclic use in multiple analyses. Template and target information:creatinine Author keywords:electrochemical impedance, Creatinine sensor, Raman spectroscopy, Molecular Imprinted Material, biosensor, label-free detection