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Reference type: Conference Proceeding
Authors: Cui WK, Zhao KY, Wei JF, Cheng GX
Publication date: 2012
Article title: Specific Rebinding of Protein Imprinted Calcium Polyacrylate/Alginate Hybrid Materials via the Adjustment of pH Values.
Page numbers: 206-209
DOI: 10.4028/ Alternative URL:

Proceedings title: Advanced Materials Research
Editors: Xu B, Li HY
Publisher: Trans Tech Publications
City: Switzerland
Volume number: 625
Conference information: Research on Mechanics, Dynamic Systems and Material Engineering

Abstract: Calcium polyacrylate/alginate (CPA/A) hybrid polymer microspheres with the imprinting of bovine serum albumin (BSA) were prepared via Ca2+ crosslinking of sodium polyacrylate (SPA), BSA and sodium alginate (SA) in inverse suspension. The specific rebinding properties of BSA imprinted hydrogel microspheres (CPA/A MIPMs) were investigated by controlling pH value from the viewpoint of adjusting the process of gelling, removing template and rebinding. The optimized pH values in gelling, removing template and rebinding process was 4.1, 8.3 and 4.2, respectively.
Template and target information: protein, bovine serum albumin, BSA
Author keywords: Hybrid hydrogel, pH Adjustment, protein molecular imprinting, Rebinding, Swelling

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