Book title: Molecular Recognition: Biotechnology, Chemical Engineering and Materials Applications
Editors: McEvoy JA
Publisher: Nova Science Publishers, Inc.
City: New York
Abstract: The 'on/off'-switched molecular recognition by a smart imprinted polymer (MIP-T) was presented in this chapter. The smart MIP-T was prepared using PNIPA as the thermosensitive element and 2-aminopurine as the template. The thermal phase transition of PNIPA induced a self-switching ability in the prepared polymer. At a relatively low temperature (such as 20 °C), the MIP-T was capable of highly specifically recognizing the imprint species, i.e., 2-aminopurine. However, above the transition temperature, the MIP-T did not demonstrate significant resolution for 2-aminopurine compared with its analogue 2-amino-6-methylpurine. Such temperature-responsive recognition, in nature, was comparable to an on/off-switched process, which allows an efficient self-regulation in the molecular recognition behavior. © 2011 Nova Science Publishers, Inc. All rights reserved
Template and target information: 2-aminopurine
Author keywords: modulation, molecular imprinting, molecular recognition, polymers