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Reference type: Conference Proceeding
Authors: Wren SP, Piletsky SA, Karim K, Gascoine P, Lacey R, Sun T, Grattan KTV
Publication date: 2014
Article title: Design and synthesis of a fluorescent molecular imprinted polymer for use in an optical fibre-based cocaine sensor.
Page numbers: 91574W-4
DOI: 10.1117/12.2059278 Alternative URL: http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1877838

Publisher: SPIE
Volume number: 9157
Conference information: Proceedings of the 23rd International Conference on Optical Fibre Sensors

Abstract: Previously, we have developed chemical sensors using fibre optic-based techniques for the detection of Cocaine, utilising molecularly imprinted polymers (MIPs) containing fluorescein moieties as the signalling groups. Here, we report the computational design of a fluorophore which was incorporated into a MIP for the generation of a novel sensor that offers improved sensitivity for Cocaine with a detection range of 1-100μM. High selectivity for Cocaine over a suite of known Cocaine interferants (25μM) was also demonstrated by measuring changes in the intensity of fluorescence signals received from the sensor
Template and target information: Cocaine

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