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Reference type: Journal
Authors: Wang CL, Hu XL, Guan P, Wu DF, Qian LW, Li J, Song RY
Article Title: Separation and purification of thymopentin with molecular imprinting membrane by solid phase extraction disks.
Publication date: 2015
Journal: Journal of Pharmaceutical and Biomedical Analysis
Volume: 102
Page numbers: 137-143.
DOI: 10.1016/j.jpba.2014.07.016
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0731708514003495

Abstract: The synthesis and performance of molecularly imprinted membranes (MIMs) as a solid phase extraction packing materials for the separation and purification of thymopentin from crude samples was described. In order to increase structural selectivity and imprinting efficiency, surface-initiated ATRP and ionic liquid (1-vinyl-3-ethyl acetate imidazolium chloride) were used to prepare molecularly imprinting membranes. The results demonstrated that solid phase extraction disks stuffed by MIMs with ionic liquids as functional monomer demonstrated high isolation and purification of performance to the thymopentin. The molecular recognition of thymopentin was analyzed by using molecular modeling software
Template and target information: thymopentin
Author keywords: Molecularly imprinting membrane, Ionic Liquids, Thymopentin, Solid phase extraction disk, Molecular simulation


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