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Reference type: Journal
Authors: Zhang CJ, Si SH, Yang ZP
Article Title: A highly selective photoelectrochemical biosensor for uric acid based on core-shell Fe3O4@C nanoparticle and molecularly imprinted TiO2.
Publication date: 2015
Journal: Biosensors and Bioelectronics
Volume: 65
Page numbers: 115-120.
DOI: 10.1016/j.bios.2014.10.013
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0956566314008008

Abstract: Combining the surface modification and molecular imprinting technique, a novel photoelectrochemical sensing platform with excellent photochemical catalysis and molecular recognition capabilities was established for the detection of uric acid based on the magnetic immobilization of Fe3O4@C nanoparticles onto magnetic glassy carbon electrode (MGCE) and modification of molecularly imprinted TiO2 film on Fe3O4@C. The developed biosensor was highly sensitive to uric acid in solutions, with a linear range from 0.3 to 34 μM and a limit of detection of 0.02 μM. Furthermore, the biosensor exhibited outstanding selectivity while used in coexisting systems containing various interferents with high concentration. The practical application of the biosensor was also realized for the selective detection of uric acid in spiked samples. The study made a successful attempt in the development of highly selective and sensitive photoelectrochemical biosensor for urine monitoring
Template and target information: uric acid
Author keywords: Photoelectrochemical biosensor, uric acid, Fe3O4@C, Molecularly imprinted TiO2, Magnetic electrode

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