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Reference type: Journal
Authors: Li LX, Ying XG, Liu JQ, Li X, Zhang WY
Article Title: Molecularly imprinted polyurethane grafted calcium alginate hydrogel with specific recognition for proteins.
Publication date: 2015
Journal: Materials Letters
Volume: 143
Page numbers: 248-251.
DOI: 10.1016/j.matlet.2014.12.108
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0167577X14022745

Abstract: Polyurethane grafted calcium alginate hydrogel microspheres intended for bovine serum albumin imprinting were prepared and characterized. The grafting modification was performed prior to the assembling of protein template with hydrogel, which was advantageous to maintain protein conformation and construct more accessible imprinted sites. It was found that the imprinted hydrogel had higher affinity to template molecules after modification. Investigations of grafting ratio influence on specific rebinding and competitive properties indicated that grafted side chains were beneficial to the selective recognition of protein
Template and target information: protein, bovine serum albumin, BSA
Author keywords: Shape memory materials, polymers, protein imprinting, polyurethane, alginate

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