MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Liu J, Song H, Liu J, Liu Y, Li L, Tang H, Li YC
Article Title: Preparation of molecularly imprinted polymer with double templates for rapid simultaneous determination of melamine and dicyandiamide in dairy products.
Publication date: 2015
Journal: Talanta
Volume: 134
Page numbers: 761-767.
DOI: 10.1016/j.talanta.2014.12.032
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0039914014010157

Abstract: In this study, a rapid and accurate determination strategy was established for simultaneous measurement of melamine (MLM) and dicyandiamide (DCD) directly in powdered milk by coupling molecularly imprinted solid-phase extraction (MISPE) with high performance liquid chromatography (HPLC). A novel double-template technique was adopted for preparing SPE packing agent and the obtained double-templated (MLM and DCD) molecularly imprinted polymers (MD-MIPs) was characterized by Fourier-transform infrared spectroscopy and scanning electron microscope (SEM). The molecular recognition ability and the binding capability of the as-prepared polymers towards MLM and DCD were evaluated via static and dynamic binding tests, and it was found that the MD-MIPs showed better affinity and selectivity for both templates compared with single-templated MIPs and non-imprinted polymers (NIPs). An approach based on MISPE and HPLC was then developed and optimized to detect MLM and DCD in powdered milk. The detection limit of the method (S/N=3) were 0.13 μg/g for MLM and 0.07 μg/g for DCD, and the relative standard deviation (RSD) of intra-day and inter-day determination for MLM was 3.3% and 4.7%, and 3.5% and 5.9% for DCD. The recoveries in MLM and DCD analysis at three spiked levels were 93.1-100.1% and 75.7-82.5%, respectively, with all RSD less than 5.2%
Template and target information: dual template, melamine, MLM, dicyandiamide, DCD
Author keywords: Double-templated molecularly imprinted polymer, solid phase extraction, Melamine, Dicyandiamide, Detection of drug residues

  Neon periodic table mug  Scientist peptide mug  I shop perodically customisable tote bag

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner