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Reference type: Journal
Authors: Lenain P, De Saeger S, Mattiasson B, Hedström M
Article Title: Affinity sensor based on immobilized molecular imprinted synthetic recognition Elements.
Publication date: 2015
Journal: Biosensors and Bioelectronics
Volume: 69
Page numbers: 34-39.
DOI: 10.1016/j.bios.2015.02.016
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0956566315001074

Abstract: An affinity sensor based on capacitive transduction was developed to detect a model compound, metergoline, in a continuous flow system. This system simulates the monitoring of low-molecular weight organic compounds in natural flowing waters, i.e. rivers and streams. During operation in such scenarios, control of the experimental parameters is not possible, which poses a true analytical challenge. A two-step approach was used to produce a sensor for metergoline. Submicron spherical molecularly imprinted polymers, used as recognition elements, were obtained through emulsion polymerization and subsequently coupled to the sensor surface by electropolymerization. This way, a robust and reusable sensor was obtained that regenerated spontaneously under the natural conditions in a river. Small organic compounds could be analyzed in water without manipulating the binding or regeneration conditions, thereby offering a viable tool for on-site application
Template and target information: metergoline
Author keywords: molecularly imprinted polymer, Capacitive Affinity Sensor, monitoring, sensors, analytical methods, Metergoline

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