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Reference type: Journal
Authors: Tang YW, Gao ZY, Wang S, Gao X, Gao JW, Ma Y, Liu XY, Li JR
Article Title: Upconversion particles coated with molecularly imprinted polymers as fluorescence probe for detection of clenbuterol.
Publication date: 2015
Journal: Biosensors and Bioelectronics
Volume: 71
Page numbers: 44-50.
DOI: 10.1016/j.bios.2015.04.005
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0956566315300178

Abstract: A novel fluorescence probe based on upconversion particles, YF3:Yb3+, Er3+, coating with molecularly imprinted polymers (MIPs@UCPs) has been synthesized for selective recognition of the analyte clenbuterol (CLB), which was characterized by scan electron microscope and X-ray powder diffraction. The fluorescence of the MIPs@UCPs probe is quenched specifically by CLB, and the effect is much stronger than the NIPs@UCPs (non-imprinting polymers, NIPs). Good linear correlation was obtained for CLB over the concentration range of 5.0-100.0 μg L-1 with a detection limit of 0.12 μg L-1 (S/N=3). The developed method was also used in the determination of CLB in water and pork samples, and the recoveries ranged from 81.66% to 102.46% were obtained with relative standard deviation of 2.96-4.98% (n=3). The present study provides a new and general tactics to synthesize MIPs@UCPs fluorescence probe with highly selective recognition ability to the CLB and is desirable for application widely in the near future
Template and target information: clenbuterol, CLB
Author keywords: Upconversion particles, molecularly imprinted polymer, Fluorescence probe, clenbuterol

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