MIPs logo MIPdatabase     MIP2018 Conference website
Custom Search
Reference type: Book Chapter
Authors: Oh J, Rhee HW, Hong JI
Publication date: 2015
Chapter title: Synthetic Receptors for Nucleosides and Nucleotides.
Chapter number: 6
Page numbers: 204-252.
DOI: 10.1039/9781782622062-00204

Book title: Synthetic Receptors for Biomolecules: Design Principles and Applications
Editors: Smith BD
Publisher: The Royal Society of Chemistry
City: Cambridge
ISBN: 978-1-84973-971-9
Series title: Monographs in Supramolecular Chemistry
Series editors: Gale P, Steed J

Abstract: Nucleosides and nucleotides have many crucial roles in biological systems as biosynthetic building blocks or as signaling molecules, and most of these processes involve molecular recognition. The chapter begins with a short summary of the chemical structures of nucleosides/nucleotides and how they are recognized by biological receptors. The focus then moves to the design of synthetic receptors for applications such as binding, membrane transport, and sensing. The classic supramolecular approach is to produce receptors that form reversible interactions with the three major nucleotide components: nucleobase, sugar, or phosphate. This is achieved using weak interactions including hydrogen bonding, aromatic stacking, or metal cation coordination. A major goal is to produce fluorescent probes for selective detection of various important nucleotides within physiological environments. Other receptor design approaches are described, including peptide libraries, diversity oriented fluorophores, molecular imprinted polymers, and hybrid sensors that are conjugates of biological receptors with appended reporter groups. The goal of the chapter is to help readers develop their own highly selective small-molecule synthetic receptors for nucleosides/nucleotides.
Template and target information: Review - synthetic receptors for nucleosides and nucleotides


  Plutonium periodic table mug  Scientist peptide mug  I shop perodically customisable tote bag

Molecules Special Issue call     Sensors Special Issue call






Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:
US listings   UK listings

Searching for Molecular Imprinting books on Amazon.com:
Molecular Imprinting
Imprinted Polymers
Polymer Chemistry
Organic Chemistry
Biosensors

Find what you need at Amazon.com

Lab supplies from Amazon