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Reference type: Journal
Authors: Suárez-Rodríguez JL, Díaz-García ME
Article Title: Fluorescent competitive flow-through assay for chloramphenicol using molecularly imprinted polymers.
Publication date: 2001
Journal: Biosensors and Bioelectronics
Volume: 16
Issue: (9-12)
Page numbers: 955-961.
DOI: 10.1016/S0956-5663(01)00243-3
Alternative URL: http://www1.elsevier.com/homepage/saa/chemmark/sd_bandB_pdfs/41.pdf

Abstract: It is a fact that molecular imprinting techniques have reached tremendous importance in the research of new artificial recognition systems. These methods resemble the mechanism of natural recognition, generally based on non-covalent interactions, but improving their stability by means of a simple and inexpensive technique, Molecular imprinting polymers (MIPs) are easily obtained by copolymerisation of suitable functional monomers and crosslinkers in the presence of the print molecule. Removal of the template leaves a polymer that selectively recognises it. In this work, different imprinted polymers for chloramphenicol (CAP) obtained using different monomers and polymerisation conditions were tested in a HPLC system, in order to obtain a highly selective material for CAP. The optimised MIP was then used as recognition phase in a fluorescent competitive flow assay to determine chloramphenicol. (C) 2001 Elsevier Science B.V. All rights reserved
Template and target information: chloramphenicol, CAP


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