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Reference type: Book Chapter
Authors: Liu YB, Huang S, Li Z, Zhao MP
Publication date: 2015
Chapter title: Molecularly Imprinted Polymers as Tools for Bioassays and Biotransformation.
Chapter number: 9
Page numbers: 207-226.
DOI: 10.1007/10_2015_315 Alternative URL: http://www.springer.com/978-3-319-20728-5

Book title: Molecularly Imprinted Polymers in Biotechnology
Editors: Mattiasson B, Ye L
Publisher: Springer
City: Berlin,Heidelberg
ISBN: 978-3-319-20728-5
Series title: Advances in Biochemical Engineering/Biotechnology

Abstract: In the past five years, significant progress has been made in preparation of various molecularly imprinted polymer (MIP)-based materials for applications in bioassays and biotransformation. This chapter reviews the important advances in these two fields. The first part mainly focuses on the development of various MIP-based bioassays that convert the rebinding of template to the imprinted cavities into measurable luminescent signals, including fluorescence, phosphorescence, Raman scattering, diffraction, and the like. In addition, MIP-based bioassays that are measured by surface plasmon resonance or quartz crystal microbalance are also discussed. In the following part, representative biotransformation reactions that make use of MIPs are summarized. In the last part of this chapter, some remaining challenges are briefly discussed for further development of the two fields
Template and target information: Review - MIPs in bioassays and biotransformations
Author keywords: Bioassay, Biotransformation, Luminescent detection, molecularly imprinted polymer, quartz crystal microbalance, surface plasmon resonance


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