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Authors: Liu KH, Liu YH, Pang R
Article Title: Determination of berberine hydrochloride in Cortex Phellodendri Chinensis with direct potential method based on molecularly imprinted polymers.
Publication date: 2015
Journal: Chinese Journal of Hospital Phamacy
Volume: 35
Issue: (13)
Page numbers: 1179-1182.
DOI: 10.13286/j.cnki.chinhosppharmacyj.2015.13.04
Alternative URL: http://118.145.16.219:81/Jwk_zgyyyx/EN/abstract/abstract8669.shtml
Abstract: OBJECTIVE To develop a method for determination of berberine hydrochloride in Cortex Phellodendri Chinensis. METHODS The berberine hydrochloride ion selective electrode was fabricated with a molecularly imprinted polymer (MIP). The process was based on synthesis of polymers with berberine hydrochloride (BH) as templates, methacrylic acid (MAA) as functional monomers, and ethylene glycol dimethacrylate (EGDMA) as a crosslinker. An ion selective electrode was prepared with this MIP as electric active substance. The content of berberine hydrochloride was calculated with working curve. RESULTS The electromotive force E exhibited a good Nernst response to berberine hydrochloride concentration C over the range of 1 x 10-6 - 1 x 10-4 mol·L-1 with a slop of 52.44 mV per decade, and the recovery was 96.9%-103.6%. CONCLUSION This method is rapid, precise and accurate, and the result is satisfactory.
Template and target information:
Author keywords: Berberine hydrochloride, cortex phellodendri chinensis, Molecularly imprinted polymers, electrode
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