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Reference type: Journal
Authors: Zhang ZJ, Wang ZZ, Wang FM, Ren JS, Qu XG
Article Title: Programmable Downregulation of Enzyme Activity Using a Fever and NIR-Responsive Molecularly Imprinted Nanocomposite.
Publication date: 2015
Journal: Small
Volume: 11
Issue: (46)
Page numbers: 6172-6178.
DOI: 10.1002/smll.201502071

Abstract: A fever and NIR-responsive molecularly imprinted nanocomposite is designed for programmable downregulation of enzyme activity. The target enzyme can be captured specifically and its activity can be downregulated only when body temperature increases abnormally. Upon NIR irradiation, the temperature of the destination region can increase accordingly inducing a further decrease in the enzyme activity
Template and target information: protein, enzyme, trypsin
Author keywords: enzyme activity regulation, molecular imprinting, NIR-responsive, photothermal, trypsin, nanocomposites

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