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Reference type: Journal
Authors: Dima SO, Dobre T, Stoica-Guzun A, Oancea F, Jinga SI, Nicolae CA
Article Title: Molecularly Imprinted Bio-Membranes Based on Cellulose Nano-Fibers for Drug Release and Selective Separations.
Publication date: 2016
Journal: Macromolecular Symposia
Volume: 359
Issue: (1)
Page numbers: 124-128.
DOI: 10.1002/masy.201400177

Abstract: The present work is a preliminary study for the preparation of molecularly imprinted membranes based on bacterial cellulose nano-fibers combined with a biodegradable natural polymer (e.g. xanthan), in order to obtain systems with high efficiency in controlled drug release and selective separations. The results evidenced a possible viable solution for obtaining biocompatible and biodegradable molecularly imprinted membranes for diosgenin, a molecule with anti-cancerous and anti-cholesterol properties. A composite material with the mass ratios between components of 1:0.5:0.1:0.05 xanthan: bacterial cellulose:citric acid:diosgenin showed interesting properties and will represent the starting point for more complex studies, like adsorption, selectivity, or controlled delivery studies
Template and target information: diosgenin
Author keywords: bioengineering, cellulose, drug delivery systems, membranes, molecular imprinting

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