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Reference type: Conference Proceeding
Authors: Webber CK, Roberts MJ
Publication date: 2002
Article title: Computational fluid dynamics models of molecularly imprinted materials in microfluidic channels.
Page numbers: 79-83
DOI: 10.1557/PROC-723-M5.1

Editors: Shea KJ, Yan M, Roberts MJ, Cremer PS, Crooks RM, Sailor MJ
Publisher: Materials Research Society
Volume number: 723
Conference information: Molecularly Imprinted Materials-Sensors And Other Devices

Abstract: Current research will lead to rapid-prototyping of chemical sensors that utilize microfabricated molecularly imprinted (MI) materials. CFD/CAD software may be used to model flow and chemical binding properties of MI materials in microfluidic channels. Use of this type of software expedites results when changes in properties are made. The surface concentration of bound analyte on a monolithic molecularly imprinted polymer (MIP) within microfluidic channels can be modeled using its experimental binding kinetics. The time necessary to reach a detection limit is calculated and optimized as a function of flow parameters. In this report, we discuss the unique issues associated with the modeling of chemical sensors that utilize MI materials


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