Abstract: A novel molecular imprinted polymer (MIP) as a SPE sorbent was synthesized for fluoxetine through a coprecipitation method. The synthesized polymer was characterized by Fourier transform infrared (FT-IR) spectroscopy and scanning electron microscopy (SEM). The kinetic and adsorption equilibrium was studied. Quantification of fluoxetine was done based on the competitive inclusion complex formation of fluoxetine with phenolphthalein-β-cyclodextrin using fiber optic linear array spectrophotometry. The method exhibited a linear dynamic range of 0.8-10.0 μg L-1 with a detection limit of 0.03 μg L-1 and a preconcentration factor of 500. The developed method was successfully applied to determine fluoxetine in various samples
Template and target information: fluoxetine, FXT
Author keywords: Magnetic solid phase extraction, molecular imprinted polymer, Graphene oxide, chitosan, Fiber optic linear array spectrophotometry, Fluoxetine