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Authors: Hubilla FAD, Mabilangan AI, Advincula RC, Del Mundo FR
Publication date: 2017
Article title: A Surface Plasmon Resonance Histamine Sensor Based on an Electropolymerized Molecularly Imprinted Polymer (E-MIP).
Page numbers: ArticleNo02006
DOI: 10.1051/matecconf/20179502006 Alternative URL: http://www.matec-conferences.org/articles/matecconf/abs/2017/09/matecconf_icmme2017_02006/matecconf_icmme2017_02006.html
Proceedings title: MATEC Web of Conferences
Volume number: 95
Conference information: 2016 the 3rd International Conference on Mechatronics and Mechanical Engineering (ICMME 2016)
Abstract: In this paper, histamine sensing by surface plasmon resonance (SPR) spectroscopy using an electropolymerized molecularly imprinted polymer (E-MIP) of functionalized polyterthiophene and histamine is reported. The MIP histamine sensor showed good linear relationship (R2 = 0.995) between the SPR angle shift and the logarithm of histamine concentration, ranging from 15 - 500 μg/mL, with a limit of detection (LOD) of 2.0 μg/mL and a calibration sensitivity of 44.6 m2 per log μg/mL histamine. Results also showed higher binding affinity of histamine for the MIP sensor than for the non-imprinted (NIP) sensor indicating excellent specificity. Moreover, the selectivity of the MIP histamine sensor against some of its structural analogues was demonstrated.
Template and target information: histamine
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