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Reference type: Book Chapter
Authors: Wulff G, Gross T, Schönfeld R, Schrader T, Kirsten C
Publication date: 1998
Chapter title: Molecular imprinting for the preparation of enzyme-analogous polymers.
Chapter number: 2
Page numbers: 10-28.
DOI: 10.1021/bk-1998-0703.ch002

Book title: Molecular and Ionic Recognition with Imprinted Polymers
Editors: Bartsch RA, Maeda M
Publisher: The American Chemical Society
City: Washington DC
Series title: ACS Symposium Series
Volume number: 703

Abstract: The principle of molecular imprinting is based on the crosslinking of a polymer in the presence of interacting monomers around a molecule that acts as a template. After removal of the template, an imprint of specific shape and with functional groups capable of chemical interactions remains in the polymer. We give an introduction into the basic principles of this method, and present new developments in our institute regarding this procedure. Recently we embarked on the development of new types of binding-site interactions which are noncovalent and stoichiometric (due to high binding constants), but do not show the disadvantages of other types of noncovalent binding. Furthermore, new catalytic systems have been designed which exhibit high esterolytic activity and Michaelis-Menten kinetics.

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