MIPdatabase
Authors: Wulff G
Publication date: 2002
Chapter title: Molecular imprinting - a way to prepare effective mimics of natural antibodies and enzymes.
Page numbers: 35-44.
Alternative URL: http://www.elsevier.com/wps/find/bookdescription.cws_home/622960/description#description
Book title: Nanoporous Materials III
Editors: Sayari A, Jaroniec M
Publisher: Elsevier
City: Amsterdam
Series title: Studies in Surface Science and Catalysis
Volume number: 141
Abstract: Molecular imprinting in synthetic polymers is used to prepare catalytically active imprinted polymers. Using different transition-state analogues of alkaline ester hydrolysis and suitable functional monomers, catalysts with strong esterolytic activity and enzyme-analogous properties are prepared. The polymers are obtained either as block polymers, and by standard suspension or mini-emulsion polymerization techniques. Through implementing the last two methods regular beads of 10 - 400 mum and minigels of 100 - 300 nm particle diameter are obtained. It is also possible to obtain soluble nanogels with diameters of 5 - 15 run, i.e. in the same dimension as natural enzymes
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