MIPs logo MIPdatabase      MIP2024 Conference banner, website is now open, register on site for important updates   
Custom Search
Reference type: Journal
Authors: Prasad BB, Pathak PK
Article Title: Development of surface imprinted nanospheres using the inverse suspension polymerization method for electrochemical ultra sensing of dacarbazine.
Publication date: 2017
Journal: Analytica Chimica Acta
Volume: 974
Page numbers: 75-86.
DOI: 10.1016/j.aca.2017.04.001
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0003267017304439

Abstract: A new ultra sensing molecularly imprinted polymer beads modified pencil graphite electrode was fabricated, with the help of the inverse suspension polymerization technique, for ascertaining the adequate supplementation of dacarbazine in the cancer treatment. The inverse suspension polymerization technique was beneficial in obtaining surface imprinted polymer-based electrocatalytic nanospheres with narrow size distribution. These nanospheres were found to be superior to the corresponding microspheres and planar films, in terms of electrode kinetics and sensitivity, with the differential pulse anodic stripping voltammetric transduction. Herein, multiwalled carbon nanotubes functionalized ester links were invoked in between the imprinted nanospheres and the pencil graphite electrode surface to secure a stable coating and better electrodics. The proposed electrochemical sensor showed the imprinting factor and the analyte adsorption coefficient as high as 24.3 and 1.06 x 10^9 L mol-1, respectively. Furthermore, 16-fold and 4-fold faster electron transfer kinetics were observed with the imprinted nanospheres than the corresponding imprinted planar film and the microspheres based electrodes, respectively. The limits of detection [0.02 (aqueous), 0.02 (plasma), 0.01 (urine), and 0.03 ng mL-1 (pharmaceutics), (3σ, RSD £ 0.23%)] of dacarbazine, realized with the imprinted polymer nanospheres, were free from any cross-reactivity and false-positive complications in aqueous, blood plasma, urine, and pharmaceutical samples
Template and target information: dacarbazine
Author keywords: Inverse suspension polymerization technique, Surface imprinted nanospheres, Functionalized multiwalled carbon nanotubes, Ester links,Pencil graphite electrode, Differential pulse anodic stripping voltammetry


  Periodic table Banana Split - the chemical formula for banana split shirt  Periodic table Bag bag  Meerkat somebody mention coffee mug






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner