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Reference type: Journal
Authors: Machtejevas E, Sellergren B, Martynaitis V, Owens PK, Maruska A
Article Title: Screening of oxazepine indole enantiomers by means of high performance liquid chromatography with imprinted polymer stationary phase.
Publication date: 2004
Journal: Journal of Separation Science
Volume: 27
Issue: (7-8)
Page numbers: 547-551.
DOI: 10.1002/jssc.200301675

Abstract: Chromatographic enantiomer separations of different oxazepine indole derivatives were performed using a molecularly imprinted polymer. A 5aP,12R,13S-trans-6,6-dimethyl-12,13-dihydro-6H- 5a,13-methanoindolo[2,1-b][1,3]naphthoxazepine-12-car-boxamide enantiomer derivative was used as a template and the resultant polymer has shown enantiomer recognition for series of template related compounds. The mechanistic description of the chiral discrimination process is scrutinised, comparing the discrimination between the different conformations and substituents of the oxazepine indoles

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