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Reference type: Book Chapter
Authors: Lei JD, Tan TW
Publication date: 2004
Chapter title: Enantioselective separation of racemic ketoprofen using molecular imprinting.
Page numbers: 735-740.
DOI: 10.1142/9789812702623_0143

Book title: Frontiers on Separation Science and Technology
Editors: Tong ZF, Kim SH
Publisher: World Scientific
ISBN: 978-981-238-916-9

Abstract: A synthetic polymer for the enantioselective separation of ketoprofen was prepared by molecular imprinting, in which 4-vinylpyridine used as functional monomer and ethylene glycol dimethacrylate were copolymerised in the presence of (S)-ketoprofen. Racemate of ketoprofen was efficiently resolved on the molecularly imprinted polymers (MIPs), a selectivity factor (alpha) of 1.51 and (S)-ketoprofen retention factor of 9.12 were obtained. Furthermore, the polymers were able to separate ketoprofen from the structurally similar ibuprofen and naproxen
Template and target information: ketoprofen


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