MIPs logo MIPdatabase    HoHoHo Use this space
Custom Search
Reference type: Book Chapter
Authors: Henthorn DB, Peppas NA
Publication date: 2004
Chapter title: Molecular simulations of recognitive polymer networks prepared by biomimetic configurational imprinting as responsive biomaterials.
Chapter number: 2
Page numbers: 7-15.
DOI: 10.1557/PROC-787-G2.1 Alternative URL: http://www.mrs.org/s_mrs/bin.asp?CID=2622&DID=60575&DOC=FILE.PDF

Book title: Molecularly Imprinted Materials-2003
Editors: Kofinas P, Sellergren B, Roberts MJ
Publisher: Materials Research Society
City: Warrendale
Series title: MRS Symposium Proceedings
Volume number: 787

Abstract: Proteins, enzymes, and antibodies have the ability to discern specific molecules out of a whole host of species and selectively bind them with remarkable affinity. A route that would enable the creation of synthetic polymers with this binding ability would be a great advance with subsequent applications in chemical sensors, single-molecule separations, and even artificial enzymes. In this work we study the molecular imprinting process whereby a controlled nanostructure consisting of distinct binding sites is created in a polymer network through a templating procedure. Simulations were done to better understand the underlying network structure that gives rise to the increased uptake. An all-atom molecular dynamics simulation was coupled with a kinetic gelation approach to study network formation in the presence of a template. The monomers used were first studied with density-functional theory in order to parameterize a force field for various methacrylates. Simulation results showed three key functional group interactions that lead to successful imprinting and subsequent rebinding

  Mug featuring the name Nicholas spelled out in symbols of the chemical elements  Lab Heroine Periodic bag  HE-MAN polymer chemistry shirt

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner