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Reference type: Journal
Authors: Kootstra PR, Kuijpers CJPF, Wubs KL, van Doorn D, Sterk SS, van Ginkel LA, Stephany RW
Article Title: The analysis of β-agonists in bovine muscle using molecular imprinted polymers with ion trap LCMS screening.
Publication date: 2005
Journal: Analytica Chimica Acta
Volume: 529
Issue: (1-2)
Page numbers: 75-81.
DOI: 10.1016/j.aca.2004.09.053
Alternative URL: http://www.sciencedirect.com/science/article/B6TF4-4DTP231-1/2/bdc438a001b5b6467b89b2974903e6d2

Abstract: A liquid chromatography-mass spectrometry (LC-MS) method for the analysis of β-agonists in bovine muscle is developed. Sample clean-up is based on molecular imprinted polymers (MIPs). The LC-MS method was validated for screening purposes. The validation results show that eight compounds (cimaterol, cimbuterol, ractopamine, clenproperol, clenbuterol, brombuterol, mabuterol, mapenterol and isoxsuprine) meet the requirements for quantitative determination using MIPs for sample clean-up. Reliable screening is possible as low as 1 μg kg-1. The method was validated for bovine muscle but also has proven to be suitable for muscle samples from rabbit, duck and turkey, liver and various kinds of fish
Template and target information: cimaterol, cimbuterol, ractopamine, clenproperol, clenbuterol, brombuterol, mabuterol, mapenterol, isoxsuprine
Author keywords: molecular imprinted polymer, beta-agonists, Growth promoter, residues, muscle


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