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Reference type: Journal
Authors: Tang YW, Huang ZF, Yang T, Hu XG, Jiang XO
Article Title: The characteristic and application of molecularly imprinted polymer: Efficient sample preconcentration of antibiotic cefathiamidine from human plasma and serum by solid phase extraction.
Publication date: 2005
Journal: Analytical Letters
Volume: 38
Issue: (2)
Page numbers: 219-226.
DOI: 10.1081/AL-200045122
Alternative URL: http://www.informaworld.com/10.1081/AL-200045122

Abstract: Polymers imprinted with cefathiamidine were synthesized using 4-vinyl-pyridine as an interacting monomer, ethyleneglycol dimethacrylate as a cross-linker, and methanol and toluene as a porogen. The polymer was used as solid-phase extraction sorbent. One-hundred percent of the cefathiamidine was bound to the polymer and the target can be eluted efficiently only by 1 ml eluant. Human plasma and serum samples were preconcentrated by the molecularly imprinted solid-phase extraction prior to analysis by HPLC. Recoveries of up to 98% were achieved. The molecularly imprinted solid phase extraction column can be used repeatedly
Template and target information: cefathiamidine
Author keywords: cefathiamidine, Molecularly imprinted polymers, Solid-phase extraction, MISPE, pre-concentration

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