MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Calmes M, Ismaili H, Jacquier R, Koudou J, Nkusi G, Zouanate A
Article Title: Supramolecular asymmetric induction : A new concept applied to the supported enantioselective synthesis of a-amino acids.
Publication date: 1990
Journal: Tetrahedron
Volume: 46
Issue: (17)
Page numbers: 6021-6032.
DOI: 10.1016/S0040-4020(01)87926-6

Abstract: A polyacrylic resin with pendant chirality has been used as a chiral auxiliary. The prochiral ester enolate, reversibly linked to the polymer chain via a Schiff base, is surrounded by chiral pendants, allowing supramolecular asymmetric induction to occur. Amino acids with enantiomeric excesses up to 88-89% could be synthesized from supported glycine t-butyl ester enolate by reaction with alkyl halides. Enantioselective protonation depends on the initial configuration of the supported aminoacid. Alanine was obtained in 90% ee by repetitive asymmetric protonation


  Periodic table Trainer shirt  PhD Scientist peptide mug  We need to talk about Kelvin shirt

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner