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Reference type: Journal
Authors: van Nostrum CF
Article Title: Molecular imprinting: A new tool for drug innovation.
Publication date: 2005
Journal: Drug Discovery Today: Technologies
Volume: 2
Issue: (1)
Page numbers: 119-124.
DOI: 10.1016/j.ddtec.2005.05.004
Alternative URL: http://igitur-archive.library.uu.nl/phar/2006-0802-202510/nostrum_05_molecular_imprinting_119_124.pdf

Abstract: Molecular imprinting is a rapidly evolving technique to prepare synthetic receptors. This paper discusses the opportunities to use such synthetic receptors for pharmaceutical applications, including separation, extraction and detection of drugs or their metabolites, and methods for drug screening, drug delivery and drug targeting. Molecularly imprinted polymers can be a valuable alternative for receptors of biological origin, such as antibodies, in terms of robustness, versatility and ease of preparation.Section editors:Daan J.A. Crommelin - Department of Pharmaceutical Sciences, Utrecht University, Utrecht, The NetherlandsGerrit Borchard - Enzon Pharmaceuticals, Piscataway, NJ, USA
Template and target information: Review - MIPs in pharmaceutical aplications


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