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Reference type: Conference Proceeding
Authors: Lee GB, Chen SJ, Huang SC, Chien FC, Chen WJ
Publication date: 2005
Article title: Microfluidic systems using localized molecular imprinting polymers for detection of nano-scale bio-molecules based on surface plasmon resonance.
Page numbers: 841-844
DOI: 10.1109/NANO.2005.1500664 Alternative URL: http://ieeexplore.ieee.org/search/wrapper.jsp?arnumber=1500664

Publisher: IEEE
City: New York
Conference information: Proceedings of 2005 5th IEEE Conference on Nanotechnology

Abstract: This paper reports a new microfluidic system integrated with localized molecular imprinting polymers (MIP) for detection of nano-scale bio-molecules based on surface plasmon resonance (SPR). The label-free bio-sensing method incorporates SPR biosensing and an innovative microfluidic biochip capable of transporting a specific amount of bio-samples inside multiple microchannels using micropumps to sensing regions where multiple MIP films are locally spun-coated such that highly-sensitive, high-throughput, and highly-specific bio-sensing of nano-scale biomolecules could be achieved. The microfluidic SPR/MIP biochips have the potential to be widely used for nano biosensing applications. While compared to large-scale SPR techniques, the developed microfluidic system has a comparable sensitivity with less consumption of samples and can perform the sensing in an automatic format.
Template and target information: cholesterol, progesterone, testosterone
Author keywords: MIP, SPR, Microfluidics, Micropumps

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