Authors: Karim K
, Breton F
, Rouillon R
, Piletska EV
, Guerreiro A
, Chianella I
, Piletsky SA
How to find effective functional monomers for effective molecularly imprinted polymers?
Publication date: 2005
Journal: Advanced Drug Delivery Reviews
Alternative URL: http://220.127.116.11/ft/18/595515/12295998.pdf
Abstract: Molecularly imprinted polymers (MIPs) are materials mimicking biological receptors in their specific recognition of analytes. Although molecular imprinting has been around for over 30 years, recently this technology has made rapid developments. However, recent investigations have led mainly to the synthesis of new polymers imprinted for a wider range of compounds without real and better understanding of the mechanisms occurring during the polymerisation and the recognition process. This review covers work developed in understanding these mechanisms and presents different strategies utilised in optimising MIP design
Template and target information: Review - MIPs design by computer modelling
Author keywords: molecularly imprinted polymer, Optimisation, molecular modelling, Monomer selection
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