MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Gomy C, Schmitzer AR
Article Title: Rational design of new polymerizable oxyanion receptors.
Publication date: 2006
Journal: Journal of Organic Chemistry
Volume: 71
Issue: (8)
Page numbers: 3121-3125.
DOI: 10.1021/jo060088k

Abstract: We report the synthesis of a library of new polymerizable functional monomers designed for complexing with the oxyanionic moiety of the chemotherapeutic drug methotrexate. The 1H NMR and ITC binding studies allowed for the selection of receptors possessing the best association parameters. Subsequently, the design of a broad library of polymerizable moiety-specific binding monomers for the imprinting of dicarboxylate containing drugs was accomplished. Di(ureidoehylenemethacrylate)stilbene possesses the highest association properties and shows potential to act as a monomer in the molecularly imprinting technique to obtain photoswitchable cavities.
Template and target information: methotrexate, N-Z-L-glutamic acid

  Krypton periodic table mug  Scientist peptide mug  I shop perodically customisable tote bag

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner