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Reference type: Journal
Authors: Piletsky SA, Nicholls IA, Rozhko MI, Sergeyeva TA, Piletska EV, El'Skaya AV, Karube I
Article Title: Molecularly imprinted polymers - Tyrosinase mimics.
Publication date: 2005
Journal: Ukrainskii Biokhimicheskii Zhurnal
Volume: 77
Issue: (6)
Page numbers: 63-67.
Alternative URL: http://ubj.biochemistry.org.ua/index.php?content=archive&article=104

Abstract: Synthetic polymers mimicking the enzyme tyrosinase have been prepared by the molecular imprinting of a complex between Cu (II) and catechol and ethyl ester of urocanic acid in an ethylene glycol dimethacrylate copolymer. Optimised polymer systems demonstrated catalysis, Michaelis-Menten kinetics and competitive inhibition similar to those of mushroom tyrosinase. The polymers benefited from superior chemical and mechanical stability in comparison with natural enzyme
Template and target information: catechol
Author keywords: molecular imprinting, polymer catalyst, Polymers-biomimics, Tyrosinase

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