MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Glad M, Reinholdsson P, Mosbach K
Article Title: Molecularly imprinted composite polymers based on trimethylolpropane trimethacrylate (TRIM) Particles for efficient enantiomeric separations.
Publication date: 1995
Journal: Reactive Polymers
Volume: 25
Issue: (1)
Page numbers: 47-54.
DOI: 10.1016/0923-1137(95)00018-E

Abstract: A convenient method to prepare spherical microparticulate composite adsorbents is described. Molecularly imprinted crosslinked methacrylate polymers were copolymerized with preformed microparticulate support particles of trimethylolpropane trimethacrylate (TRIM) containing residual double bonds. The resulting composite adsorbent could be packed in HPLC columns after just a simple washing procedure and was used for efficient chiral separation of amino acid derivatives. The pore system of the TRIM- particles could be filled with large amounts of functional polymer. The enantioselectivity for the print molecule Boc-L-Phe-OH was in the same range as that obtained by traditional bulk phase molecular imprinting, while the performance in HPLC was improved, both in terms of efficiency and pressure stability. The effect of various degrees of crosslinking and of monomer concentration on polymer characteristics, such as porosity and specific surface area, and its impact on the structure of the final polymer is discussed as well as the chromatographic performance of the resulting matrices

  Mug featuring the name Klaus spelled out in symbols of the chemical elements  Scientist peptide mug  I shop perodically customisable tote bag

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner