MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Ye L, Yoshimatsu K, Kolodziej D, Da Cruz Francisco J, Dey ES
Article Title: Preparation of molecularly imprinted polymers in supercritical carbon dioxide.
Publication date: 2006
Journal: Journal of Applied Polymer Science
Volume: 102
Issue: (3)
Page numbers: 2863-2867.
DOI: 10.1002/app.24648
Alternative URL: http://teresacasimiro.com.sapo.pt/Bibliographic_References/23.pdf

Abstract: Molecularly imprinted polymer nanoparticles were prepared in supercritical carbon dioxide using a noncovalent imprinting approach. In the present work, propranolol was used as a model template, methacrylic acid as a functional monomer, and divinylbenzene as a crosslinker. Under a high dilution condition, the heterogeneous polymerization resulted in discrete crosslinked polymer nanoparticles. Compared with the nonimprinted polymers, the imprinted nanoparticles displayed much higher propranolol uptake in a low polarity organic solvent. The use of a single enantiomer (S)-propranolol as the template clearly demonstrated that the imprinted binding sites are chiral-selective, with a cross-reactivity towards (R)-propranolol of less than 5%. The overall binding performance of the imprinted nanoparticles was comparable to imprinted polymers prepared in conventional organic solvents. 2006 Wiley Periodicals, Inc. J Appl Polym Sci 102: 2863-2867, 2006
Template and target information: (S)-propranolol, propranolol
Author keywords: molecular imprinting, Supercritical carbon dioxide, propranolol


  Double Bonds spoof movie poster mug  Chemistry peptide mug    Shirt featuring the template Propranolol

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner