MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Puoci F, Cirillo G, Curcio M, Iemma F, Spizzirri UG, Picci N
Article Title: Molecularly imprinted solid phase extraction for the selective HPLC determination of α-tocopherol in bay leaves.
Publication date: 2007
Journal: Analytica Chimica Acta
Volume: 593
Issue: (2)
Page numbers: 164-170.
DOI: 10.1016/j.aca.2007.04.053
Alternative URL: http://www.sciencedirect.com/science/article/B6TF4-4NMC8BS-4/2/ced6486e78737c6cbf07718d7a476eea

Abstract: A new sorbent for molecularly imprinted solid phase extraction (MISPE) was synthesized to extract and purify α-tocopherol (α-TP) from vegetable sources. Molecularly imprinted polymers (MIP) were synthesized using methacrylic acid (MAA) as functional monomer and ethylene glycol dimethacrylate (EGDMA) as crosslinking agent using a photo-polymerization procedure. A thermo-polymerization was also performed but no imprinting effect in the resulting materials was raised. The proposed MISPE protocol could overcome the drawback of traditional detection methods, which require pre-treatments of the samples. The possibility to obtain the selective recognition of α-TP from natural samples in aqueous mixtures represents one of the main advantages of our materials. Our procedure involves the direct HPLC injection of eluate without any treatment and above all the use of no toxic and biocompatible organic solvents. After the evaluation of the selectivity of the α-TP imprinted polymers, the performance of these materials as solid phase extraction (SPE) sorbents was investigated. Our MISPE-HPLC procedure has a high sensitivity, LOD and LOQ were 3.49 x 10-7 and 1.16 x 10-6 mol L-1, respectively, as well as good precision (intraday precision below 3.3% and interday precisions below 6.5%) and recovery (60%). Thus, it can be successfully used for the purification of α-TP from bay leaves
Template and target information: α-tocopherol, α-TP, vitamin E
Author keywords: α-Tocopherol, MIP, selective extraction, Bay, food analysis

  Hat featuring the name Francesco spelled out in symbols of the chemical elements  Lab Hero Periodic tablemug  HE-MAN polymer chemistry shirt

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner