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Reference type: Journal
Authors: Li L, Wu WX, Yang GL
Article Title: Molecularly Imprinted Polymer as Stationary Phase in HPLC for the Separation and Recognition of Sulfamethoxazole.
Publication date: 2007
Journal: Journal of Instrumental Analysis
Volume: 26
Issue: (3)
Page numbers: 409-412.
Alternative URL: http://en.cnki.com.cn/Article_en/CJFDTotal-TEST200703030.htm

Abstract: Sulfamethoxazole was used as a template for the in-situ preparation of molecular imprinted polymer(MIP) rods as stationary phases in HPLC for the separation and recognition of sulfamethoxazole and its analogues.It was found that the interactions between the MIP and target molecules were not only due to the hydrogen-bonding action but also due to hydrophobic interaction in the imprinted area.The effects of water content and flow rate on the separation were studied.Experimental results showed that the sulfamethoxazole imprinted polymer rod has specific selectivity and high affinity to sulfamethoxazole and its analogues.
Author keywords: in-situ polymerization method, molecular imprinting, sulfamethoxazole, stationary phase, molecularly imprinted polymer


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