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Reference type: Journal
Authors: Petrukhin OM, Pogorelova SP, Kharitonov AB, Shipulo EV
Article Title: Molecularly selective field-effect transistors for determining nicotinamide adenine dinucleotide and its phosphates.
Publication date: 2007
Journal: Journal of Analytical Chemistry
Volume: 62
Issue: (9)
Page numbers: 894-902.
DOI: 10.1134/S106193480709016X

Abstract: Molecularly selective field-effect transistors are developed for determining oxidized and reduced forms of nicotinamide adenine dinucleotides (NAD+ and NADH) and their phosphates (NAD(P)+ and NAD(P)H). Copolymers of acrylamide and acrylamidophenylboric acid imprinted with corresponding nucleotides are used as sensing elements of sensors. After washing out a nucleotide, a cavity corresponding to the surface of the imprinted nucleotide is retained and ensures the selectivity of the sensor. At the same time, sensors containing any of the nucleotides of interest in solutions demonstrate almost equal sensitivities of 10-7 M. The properties of the sensors are explained by the structure of the nucleotides and the composition of the membranes
Template and target information: nicotinamide adenine dinucleotides, NAD+, NADH, NAD(P)+, NAD(P)H


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