MIPdatabase
Authors: Chen FQ, Liu SX, Fang Y, Wang YJ, Zhang ZY, Jiang Y
Article Title: Preparation of molecularly imprinted polymer microspheres and their recognition for chenodeoxycholic acid.
Publication date: 2007
Journal: Chemical Journal of Chinese Universities
Volume: 28
Issue: (11)
Page numbers: 2195-2199.
Alternative URL: http://www.cjcu.jlu.edu.cn/CN/abstract/abstract10345.shtml
Abstract: Molecularly imprinted polymer microspheres were obtained by deposition polymerization with methyacrylic acid(MAA) as the functional monomer, trimethylolproparte trimethacrylate (TRIM) and ethylene glycoldimethacrylate(EDGMA) as the cross-linkers, chenodeoxycholic acid(CDCA) as the template molecule, and 2,2-azobis-isobutyronitrile as the initiation agent. The average size of the molecularly imprinted polymer microspheres was between 200 nm and 300 nm. The binding properties of the template molecule on MIPMS were evaluated by Scatchard analysis. The selective adsorptions of target molecule on MIPMS were studied. The results indicate that there were, two class binding sites in polymers and the MIPMS showed a specfic affinity toward chenodeoxycholic acid
Template and target information: chenodeoxycholic acid, CDCA
Author keywords: deposition polymerization, molecularly imprinted polymeric microsphere, molecular recognition, Chenodeoxycholic acid
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