MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Diltemiz SE, Say RI, Büyüktiryaki S, Hür D, Denizli A, Ersöz A
Article Title: Quantum dot nanocrystals having guanosine imprinted nanoshell for DNA recognition.
Publication date: 2008
Journal: Talanta
Volume: 75
Issue: (4)
Page numbers: 890-896.
DOI: 10.1016/j.talanta.2007.12.036
Alternative URL: http://www.sciencedirect.com/science/article/B6THP-4RH94R3-2/1/d8e1ce922f33965a3f5e192918788085

Abstract: Molecular imprinted polymers (MIPs) as a recognition element for sensors are increasingly of interest and MIP nanoparticles have started to appear in the literature. In this study, we have proposed a novel thiol ligand-capping method with polymerizable methacryloylamido-cysteine (MAC) attached to CdS quantum dots (QDs), reminiscent of a self-assembled monolayer and have reconstructed surface shell by synthetic host polymers based on molecular imprinting method for DNA recognition. In this method, methacryloylamidohistidine-platinium (MAH-Pt(II)) is used as a new metal-chelating monomer via metal coordination-chelation interactions and guanosine templates of DNA. Nanoshell sensors with guanosine templates give a cavity that is selective for guanosine and its analogues. The guanosine can simultaneously chelate to Pt(II) metal ion and fit into the shape-selective cavity. Thus, the interaction between Pt(II) ion and free coordination spheres has an effect on the binding ability of the CdS QD nanosensor. The binding affinity of the guanosine imprinted nanocrystals has investigated by using the Langmuir and Scatchard methods, and experiments have shown the shape-selective cavity formation with O6 and N7 of a guanosine nucleotide (Kaá=á4.841á+á106ámoláL-1) and a free guanine base (Kaá=á0.894á+á106ámoláL-1). Additionally, the guanosine template of the nanocrystals is more favored for single stranded DNA compared to double stranded DNA
Author keywords: Quantum dots, Nanoshell sensor, Molecularly imprinted polymers, Deoxtribo nucleic acid (DNA) recognition, Photoluminescence

  Eat, sleep, imprint, repeat magnet  Mug featuring the name Adil spelled out in the single letter amino acid code  Man of proper-tea mug in blue

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner