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Reference type: Book Chapter
Authors: Collins BE, Wright AT, Anslyn EV
Publication date: 2007
Chapter title: Combining molecular recognition, optical detection, and chemometric analysis.
Page numbers: 181-218.
DOI: 10.1007/128_2007_114

Book title: Creative Chemical Sensor Systems
Editors: Schrader T
Publisher: Springer
City: Berlin
ISBN: 0340-1022
Series title: Topics in Current Chemistry
Volume number: 277

Abstract: The mammalian olfactory and gustatory systems have inspired an emergent area of molecular recognition, which utilizes arrays of semiselective sensors to create patterns to distinguish analytes. Pattern-based recognition, combined with chemometric analysis, has provided chemists the tools necessary to create sensing ensembles that far exceed our ability to rationally design and synthesize sensors for complex molecules. These differential sensing arrays have been used for several biological, environmental, and industrial applications, and are becoming increasingly relevant to real world problems. Herein, we will examine the progress that has been made through differential molecular recognition. We will also discuss the different array platforms that have been employed and provide a brief introduction to the most commonly used chemometric analytical methods
Author keywords: Chemometric analysis, Colorimetric sensing, Differential arrays, pattern recognition

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