Book title: Handbook of Biosensors and Biochips
Editors: Marks RS, Cullen DC, Karube I, Lowe CR, Weetall HH
Abstract: Molecular imprinted polymers (MIPs) have been prepared using a variety of monomeric substrates for the production of polymers containing imprints of small molecules. We have shown that in some cases, the MIP is not an imprinted polymer but an ion-specific system. Preparation of MIPs using resorcinol/phenylenediamine produces, analyte-specific electrodes that act as MIPs but appear more like organic ion exchange electrodes. These data suggest that greater care must be taken in future studies of MIPs with regard to mechanism of action.
Template and target information: resorcinol